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Article

The 460Trp allele of alpha-adducin increases carotid intima-media thickness in young adult males.

Journal of hypertension - 1 Apr 2006

Sarzani Riccardo, Cusi Daniele, Salvi Fabio, Barlassina Cristina, Macciardi Fabio, Pietrucci Francesca, Cola Giovanna, Catalini Roberto, Dal Fiume Chiara, Dessì-Fulgheri Paolo, Rappelli Alessandro

Abstract excerpt

BACKGROUND: The 460Trp allele of the alpha-adducin gene (ADD1), which is involved in a form of salt-sensitive hypertension, has been associated with patterns of target organ damage. OBJECTIVES: As carotid artery intima-media thickness (IMT) largely depends upon unknown genetic factors, besides being associated to conventional risk factors, we tested the association of the 460Trp allele of ADD1 with IMT in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16531798
DOI: 10.1097/01.hjh.0000217852.89745.dc

Genes

ADD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The 460Trp allele of alpha-adducin increases carotid intima-media thickness in young adult males.PMID 16531798Read ↗

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