Article
Dicer-related drh-3 gene functions in germ-line development by maintenance of chromosomal integrity in Caenorhabditis elegans.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Sept 2007
Nakamura Masaharu, Ando Rumi, Nakazawa Taro, Yudazono Takuro, Tsutsumi Naoko, Hatanaka Naoki, Ohgake Toshiyasu, Hanaoka Fumio, Eki Toshihiko
Abstract excerpt
In the course of systematic RNA interference (RNAi)-based screens with helicase-like genes in Caenorhabditis elegans, we have identified the drh-3(D2005.5) gene as a candidate gene for protection against X-ray irradiation. This gene encodes a novel RNA helicase-like protein that is similar to two nematode Dicer-related helicases (DRH). Here, we have showed the increased expression of drh-3 transcripts during...
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