Article
Effect of tolterodine on sleep structure modulated by CYP2D6 genotype.
Sleep medicine - 1 Jul 2008
Diefenbach Konstanze, Jaeger Katrin, Wollny Agnes, Penzel Thomas, Fietze Ingo, Roots Ivar
Abstract excerpt
OBJECTIVE: Tolterodine, a drug for the treatment of overactive bladder symptoms, has a limited entry into the brain, which makes cognitive side effects seldom. However, some case reports have described central-nervous side effects such as sleepiness. The aim of this retrospective analysis was to investigate whether tolterodine-related effects on sleep stage parameters could be explained by different CYP2D6...
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