Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paroxetine-induced conversion of cytochrome P450 2D6 phenotype and occurence of adverse effects.

General physiology and biophysics - 1 Mar 2003

Zourková A, Hadasová E

Abstract excerpt

The paper is focused on a comparison of the distribution of side effects of treatment with paroxetine within a group of 30 patients genotyped and phenotyped for their CYP 2D6 metabolic status. Genotyping procedure showed that the patient group did not include any individual with poor metabolizer (PM) genotype; on the other hand, most patients (24) were classified as PMs by virtue of their phenotype, which...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antidepressive Agents, Second-Generation
Share to Cytochrome P-450 CYP2D6

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression

Share to Genotype

Share to Paroxetine

Share to Phenotype

Share to Treatment Outcome

Source

Identifiers

PMID: 12870705

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paroxetine-induced conversion of cytochrome P450 2D6 phenotype and occurence of adverse effects.PMID 12870705Read ↗

Links among paroxetine-induced sexual dysfunctions, gender, and CYP2D6 activity.Semantic proximity Read ↗

Drug extrapyramidal side effects. CYP2D6 genotypes and phenotypes.Semantic proximity Read ↗

Miotic action of tramadol is determined by CYP2D6 genotype.Semantic proximity Read ↗

Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test.Semantic proximity Read ↗

[Acute dyskinetic syndrome during chloropromazine treatment of a female patient with CYP2D6 poor metabolism phenotype].Semantic proximity Read ↗

Paroxetine steady-state plasma concentration in relation to CYP2D6 genotype in extensive metabolizers.Semantic proximity Read ↗

Effect of cytochrome P450 2D6 genotype on maternal paroxetine plasma concentrations during pregnancy.Semantic proximity Read ↗

Drug extrapyramidal side-effects or not: is there a dextromethorphan phenotype difference?Semantic proximity Read ↗

Reboxetine and cytochrome P450--comparison with paroxetine treatment in humans.Semantic proximity Read ↗

Severe adverse effects in a newborn with two defective CYP2D6 alleles after exposure to paroxetine during late pregnancy.Semantic proximity Read ↗

Tolerance to desvenlafaxine in rapid metabolizing depressed patients.Semantic proximity Read ↗

Effect of tolterodine on sleep structure modulated by CYP2D6 genotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.