Article
The pharmacokinetic profile of fesoterodine 8 mg with daytime or nighttime dosing.
European journal of clinical pharmacology - 1 Feb 2010
Malhotra Bimal K, Crownover Penelope H, LaBadie Robert, Glue Paul, MacDiarmid Scott A
Abstract excerpt
PURPOSE: Diurnal variation can affect drug pharmacokinetics. Fesoterodine is a new antimuscarinic drug for the treatment of overactive bladder (OAB). We estimated the relative bioavailability of 5-hydroxymethyl tolterodine (5-HMT), the active metabolite of fesoterodine, following nighttime and da...
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