Article
Residual effects of esmirtazapine on actual driving performance: overall findings and an exploratory analysis into the role of CYP2D6 phenotype.
Psychopharmacology - 1 May 2011
Ramaekers Johannes G, Conen Silke, de Kam Pieter Jan, Braat Sabine, Peeters Pierre, Theunissen Eef L, Ivgy-May Neely
Abstract excerpt
INTRODUCTION: Esmirtazapine is evaluated as a novel drug for treatment of insomnia. PURPOSE: The present study was designed to assess residual effects of single and repeated doses of esmirtazapine 1.5 and 4.5 mg on actual driving in 32 healthy volunteers in a double-blind, placebo-controlled study. Treatment with single doses of zopiclone 7.5 mg was included as active control. METHODS: Treatments were...
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