Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The APC E1317Q and I1307K polymorphisms in non-colorectal cancers.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Oct 2007

Liberman Eliezer, Kraus Sarah, Sagiv Eyal, Dulkart Oleg, Kazanov Dina, Arber Nadir

Abstract excerpt

Mutation of the adenomatous polyposis coli (APC) gene is an important initiating factor in the early stages of the multi-step colorectal cancer (CRC) carcinogenesis. APC E1317Q and I1307K variants have been linked to CRC. The aim of this study was to examine the association of these variants with non-colorectal cancers. Mutation screening was performed using real-time PCR. The APC E1317Q variant was detected in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Neoplasm
Share to Gene Frequency
Share to Genes, APC

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Heterozygote

Share to Neoplasms

Share to Polymorphism, Genetic

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 17920230
DOI: 10.1016/j.biopha.2007.08.016

Genes

APC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The APC E1317Q and I1307K polymorphisms in non-colorectal cancers.PMID 17920230Read ↗

Association of APC I1307K and E1317Q polymorphisms with colorectal cancer among Egyptian subjects.Semantic proximity Read ↗

The APC E1317Q variant in adenomatous polyps and colorectal cancers.Semantic proximity Read ↗

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317QSemantic proximity Read ↗

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.Semantic proximity Read ↗

Inherited Colorectal Polyposis and Cancer Risk of the APC I1307K PolymorphismSemantic proximity Read ↗

Position statement of the International Society for Gastrointestinal Hereditary Tumours (InSiGHT) on APC I1307K and cancer risk.Semantic proximity Read ↗

Detailed molecular genetics of the APC*E1317Q mutation in tumor tissue suggest it may not be pathologically significant.Semantic proximity Read ↗

APC E1317Q is not associated with Colorectal Cancer in a population-based case-control study in Northern Israel.Semantic proximity Read ↗

Phenotypic characteristics of colo-rectal cancer in I1307K APC germline mutation carriers compared with sporadic cases.Semantic proximity Read ↗

Risk of colorectal neoplasia associated with the adenomatous polyposis coli E1317Q variant.Semantic proximity Read ↗

The impact of APC polymorphisms on the transition from polyps to colorectal cancer (CRC).Semantic proximity Read ↗

APC gene loss of heterozygosity, mutations, E1317Q, and I1307K germ-line variants in sporadic colon cancer in Croatia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.