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Article

Detailed molecular genetics of the APC*E1317Q mutation in tumor tissue suggest it may not be pathologically significant.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2013

Zauber Peter, Marotta Stephen P, Sabbath-Solitare Marlene

Abstract excerpt

APC*E1317Q is a low-penetrance variant of the APC gene suggested as a risk for the development of colorectal adenomas and carcinomas. There is very little in the literature describing the molecular details of APC*E1317Q in tumor tissue. We provide information about the molecular genetics of 3 patients with APC*E1317Q. For 1 patient, we show linkage to a specific APC allele. We further show that loss of...

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PMID: 23846443
DOI: 10.1097/PDM.0b013e3182830889

Genes

APC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Detailed molecular genetics of the APC*E1317Q mutation in tumor tissue suggest it may not be pathologically significant.PMID 23846443Read ↗

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