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Article

APC E1317Q is not associated with Colorectal Cancer in a population-based case-control study in Northern Israel.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Nov 2006

Rozek Laura S, Rennert Gad, Gruber Stephen B

Abstract excerpt

A variant in the adenomatous polyposis coli gene, APC E1317Q, has been inconsistently associated with risk of colorectal cancer. We used data collected as a part of the Molecular Epidemiology of Colorectal Cancer study, a population-based study of colorectal cancer in northern Israel (1,834 matched cases and controls), to evaluate the relationship between this variant and risk of sporadic colorectal cancer. There...

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PMID: 17119068
DOI: 10.1158/1055-9965.EPI-06-0504

Genes

APC

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

APC E1317Q is not associated with Colorectal Cancer in a population-based case-control study in Northern Israel.PMID 17119068Read ↗

Risk of colorectal neoplasia associated with the adenomatous polyposis coli E1317Q variant.Semantic proximity Read ↗

The APC E1317Q variant in adenomatous polyps and colorectal cancers.Semantic proximity Read ↗

Genetic analyses in consecutive israeli jewish colorectal cancer patients.Semantic proximity Read ↗

The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.Semantic proximity Read ↗

The APC E1317Q and I1307K polymorphisms in non-colorectal cancers.Semantic proximity Read ↗

Detailed molecular genetics of the APC*E1317Q mutation in tumor tissue suggest it may not be pathologically significant.Semantic proximity Read ↗

Germline APC variants in patients with multiple colorectal adenomas, with evidence for the particular importance of E1317QSemantic proximity Read ↗

Association of APC I1307K and E1317Q polymorphisms with colorectal cancer among Egyptian subjects.Semantic proximity Read ↗

The APC gene I1307K variant is rare in Norwegian patients with familial and sporadic colorectal or breast cancer.Semantic proximity Read ↗

Clinical and screening implications of the I1307K adenomatous polyposis coli gene variant in Israeli Ashkenazi Jews with familial colorectal neoplasia. Evidence for a founder effect.Semantic proximity Read ↗

The I1307K adenomatous polyposis coli gene variant does not contribute in the assessment of the risk for colorectal cancer in Ashkenazi Jews.Semantic proximity Read ↗

The APC p.I1307K polymorphism is a significant risk factor for CRC in average risk Ashkenazi Jews.Semantic proximity Read ↗

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