Article
Zebrafish melanophilin facilitates melanosome dispersion by regulating dynein.
Current biology : CB - 23 Oct 2007
Sheets Lavinia, Ransom David G, Mellgren Eve M, Johnson Stephen L, Schnapp Bruce J
Abstract excerpt
BACKGROUND: Fish melanocytes aggregate or disperse their melanosomes in response to the level of intracellular cAMP. The role of cAMP is to regulate both melanosome travel along microtubules and their transfer between microtubules and actin. The factors that are downstream of cAMP and that directly modulate the motors responsible for melanosome transport are not known. To identify these factors, we are...
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