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Hepatitis C virus envelope glycoprotein immunization of rodents elicits cross-reactive neutralizing antibodies.

Vaccine - 7 Nov 2007

Stamataki Zania, Coates Stephen, Evans Matthew J, Wininger Mark, Crawford Kevin, Dong Christine, Fong Yiu-Lian, Chien David, Abrignani Sergio, Balfe Peter, Rice Charles M, McKeating Jane A, Houghton Michael

Abstract excerpt

Neutralizing antibody responses elicited during infection generally confer protection from infection. Hepatitis C virus (HCV) encodes two glycoproteins E1 and E2 that are essential for virus entry and are the major target for neutralizing antibodies. To assess whether both glycoproteins are required for the generation of a neutralizing antibody response, rodents were immunized with a series of glycoproteins...

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Identifiers

PMID: 17919789
DOI: 10.1016/j.vaccine.2007.08.053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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