Article
Polymorphism of interleukin-18 promoter influences the onset of kidney graft function after transplantation.
Tissue antigens - 1 Nov 2007
Kolesar L, Novota P, Krasna E, Slavcev A, Viklicky O, Honsova E, Striz I
Abstract excerpt
It has been well recognized that the promoter polymorphisms of interleukin-18 (IL-18) influence the level of cytokine expression. In our previously published data, we showed constitutive IL-18 expression in the epithelium of renal distal tubules in patients after kidney transplantation and significantly elevated IL-18 expression during acute rejection. In this study, we evaluated the clinical significance of two...
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