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Article

Breed relationships facilitate fine-mapping studies: a 7.8-kb deletion cosegregates with Collie eye anomaly across multiple dog breeds.

Genome research - 1 Nov 2007

Parker Heidi G, Kukekova Anna V, Akey Dayna T, Goldstein Orly, Kirkness Ewen F, Baysac Kathleen C, Mosher Dana S, Aguirre Gustavo D, Acland Gregory M, Ostrander Elaine A

Abstract excerpt

The features of modern dog breeds that increase the ease of mapping common diseases, such as reduced heterogeneity and extensive linkage disequilibrium, may also increase the difficulty associated with fine mapping and identifying causative mutations. One way to address this problem is by combining data from multiple breeds segregating the same trait after initial linkage has been determined. The multibreed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17916641
DOI: 10.1101/gr.6772807
PMCID: PMC2045139

Genes

NHEJ1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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