Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linkage disequilibrium mapping in domestic dog breeds narrows the progressive rod-cone degeneration interval and identifies ancestral disease-transmitting chromosome.

Genomics - 1 Nov 2006

Goldstein Orly, Zangerl Barbara, Pearce-Kelling Sue, Sidjanin Duska J, Kijas James W, Felix Jeanette, Acland Gregory M, Aguirre Gustavo D

Abstract excerpt

Canine progressive rod-cone degeneration (prcd) is a retinal disease previously mapped to a broad, gene-rich centromeric region of canine chromosome 9. As allelic disorders are present in multiple breeds, we used linkage disequilibrium (LD) to narrow the approximately 6.4-Mb interval candidate region. Multiple dog breeds, each representing genetically isolated populations, were typed for SNPs and other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breeding
Share to Chromosomes, Artificial, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Complementary

Share to Dog Diseases

Share to Linkage Disequilibrium

Share to Retinal Degeneration

Share to Species Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 16859891
DOI: 10.1016/j.ygeno.2006.05.013
PMCID: PMC4006154

Genes

GRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linkage disequilibrium mapping in domestic dog breeds narrows the progressive rod-cone degeneration interval and identifies ancestral disease-transmitting chromosome.PMID 16859891Read ↗

Canine RD3 mutation establishes rod-cone dysplasia type 2 (rcd2) as ortholog of human and murine rd3.Semantic proximity Read ↗

Linkage analysis and comparative mapping of canine progressive rod-cone degeneration (prcd) establishes potential locus homology with retinitis pigmentosa (RP17) in humans.Semantic proximity Read ↗

Cloning and characterization of canine SHARP1 and its evaluation as a positional candidate for canine early retinal degeneration (erd).Semantic proximity Read ↗

Identification of a RAPD marker linked to progressive rod-cone degeneration in dogs.Semantic proximity Read ↗

Late-onset progressive retinal atrophy in the Gordon and Irish Setter breeds is associated with a frameshift mutation in C2orf71.Semantic proximity Read ↗

Elucidating the genetic basis of canine progressive retinal atrophies in several breeds of dogSemantic proximity Read ↗

Canine CNGB3 mutations establish cone degeneration as orthologous to the human achromatopsia locus ACHM3.Semantic proximity Read ↗

Genetic mapping of canine multiple system degeneration and ectodermal dysplasia loci.Semantic proximity Read ↗

Canine inherited retinal degenerations: update on molecular genetic research and its clinical application.Semantic proximity Read ↗

A deletion in nephronophthisis 4 (NPHP4) is associated with recessive cone-rod dystrophy in standard wire-haired dachshund.Semantic proximity Read ↗

A CNGB1 Frameshift Mutation in Papillon and Phalène Dogs with Progressive Retinal AtrophySemantic proximity Read ↗

A non-stop S-antigen gene mutation is associated with late onset hereditary retinal degeneration in dogs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.