Article
Association study of candidate genes for primary cataracts and fine-mapping of a candidate region on dog chromosome 1 in Entlebucher mountain dogs.
Molecular vision - 16 May 2008
Müller Christina, Distl Ottmar
Abstract excerpt
PURPOSE: The Entlebucher mountain dog (EMD) shows a high incidence of primary non-congenital cataracts (CAT). Because of the late-onset of CAT, it is difficult to exclude affected animals from breeding. A screen of candidate genes should help to identify the genes associated with CAT in EMD. METHODS: We genotyped 39 flanking microsatellite markers for 31 cataract candidate genes in 10 EMD families and tested them...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.