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Article

Variants in Nebulin (NEB) Are Linked to the Development of Familial Primary Angle Closure Glaucoma in Basset Hounds.

PloS one - 1 Jan 2015

Ahram Dina F, Grozdanic Sinisa D, Kecova Helga, Henkes Arjen, Collin Rob W J, Kuehn Markus H

Abstract excerpt

Several dog breeds are susceptible to developing primary angle closure glaucoma (PACG), which suggests a genetic basis for the disease. We have identified a four-generation Basset Hound pedigree with characteristic autosomal recessive PACG that closely recapitulates PACG in humans. Our aim is to...

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Identifiers

PMID: 25938837
DOI: 10.1371/journal.pone.0126660
PMCID: PMC4418656

Genes

NEB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-25938837-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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