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Article

Structural methods for studying IRES function.

Methods in enzymology - 1 Jan 2007

Kieft Jeffrey S, Costantino David A, Filbin Megan E, Hammond John, Pfingsten Jennifer S

Abstract excerpt

Internal ribosome entry sites (IRESs) substitute RNA sequences for some or all of the canonical translation initiation protein factors. Therefore, an important component of understanding IRES function is a description of the three-dimensional structure of the IRES RNA underlying this mechanism. This includes determining the degree to which the RNA folds, the global RNA architecture, and higher resolution...

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PMID: 17913644
DOI: 10.1016/S0076-6879(07)30013-X

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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