Article
Genetic background of anticyclic citrullinated peptide autoantibody production in Hungarian patients with rheumatoid arthritis.
Annals of the New York Academy of Sciences - 1 Sept 2007
Poór Gyula, Nagy Zsolt B, Schmidt Zsuzsanna, Brózik Márta, Merétey Katalin, Gergely Péter
Abstract excerpt
Polymorphisms of the peptidylarginine deiminase 4 (PADI4) gene encoding for the isoenzyme that converts arginyl into citrullyl residues have been shown to contribute to susceptibility to rheumatoid arthritis (RA), depending on the population studied. We aimed at determining whether PADI4 single nucleotide polymorphisms (SNPs) are associated with RA in a Hungarian population. The relationship between anticyclic...
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