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Article

Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case-control study.

Arthritis research & therapy - 1 Jan 2006

Hoppe Berthold, Häupl Thomas, Gruber Rudolf, Kiesewetter Holger, Burmester Gerd R, Salama Abdulgabar, Dörner Thomas

Abstract excerpt

Peptidylarginine deiminase type 4 (PADI4) genotypes were shown to influence susceptibility to rheumatoid arthritis (RA) in the Japanese population. Such an association could not previously be confirmed in different European populations. In the present study, we analysed exons 2-4 of PADI4 in 102 German RA patients and 102 healthy individuals to study the influence of PADI4 variability on RA susceptibility by...

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Source

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Identifiers

PMID: 16469113
DOI: 10.1186/ar1889
PMCID: PMC1526594

Genes

PADI4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case-control study.PMID 16469113Read ↗

A functional haplotype of PADI4 gene in rheumatoid arthritis: positive correlation in a French population.Semantic proximity Read ↗

A functional haplotype of the PADI4 gene associated with increased rheumatoid arthritis susceptibility in Koreans.Semantic proximity Read ↗

High variability of peptidylarginine deiminase 4 (PADI4) in a healthy white population: characterization of six new variants of PADI4 exons 2-4 by a novel haplotype-specific sequencing-based approach.Semantic proximity Read ↗

Polymorphisms and functional haplotype in PADI4: further evidence for contribution on rheumatoid arthritis susceptibility and anti-cyclic citrullinated peptide antibodies in a western Mexican population.Semantic proximity Read ↗

PADI4 polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis.Semantic proximity Read ↗

PADI4 polymorphisms and the functional haplotype are associated with increased rheumatoid arthritis susceptibility: A replication study in a Southern Mexican population.Semantic proximity Read ↗

Associations Between PADI4 Gene Polymorphisms and Rheumatoid Arthritis: An Updated Meta-analysis.Semantic proximity Read ↗

A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population.Semantic proximity Read ↗

[The significance of serum peptidylarginine deiminase 4 in rheumatoid arthritis].Semantic proximity Read ↗

Peptidylarginine deiminase type 4: identification of a rheumatoid arthritis-susceptible gene.Semantic proximity Read ↗

Influence of peptidylarginine deiminase type 4 genotype and shared epitope on clinical characteristics and autoantibody profile of rheumatoid arthritis.Semantic proximity Read ↗

PADI4 polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

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