Article
A functional haplotype of PADI4 gene in rheumatoid arthritis: positive correlation in a French population.
The Journal of rheumatology - 1 May 2009
Gandjbakhch Frédérique, Fajardy Isabelle, Ferré Benjamin, Dubucquoi Sylvain, Flipo René-Marc, Roger Nadine, Solau-Gervais Elisabeth
Abstract excerpt
OBJECTIVE: A functional haplotype of peptidyl arginine deiminase 4 (PADI4) was associated with susceptibility to rheumatoid arthritis (RA) in Asian populations, but the results are contradictory in Europeans. We investigated (1) the association of 2 single-nucleotide polymorphisms (SNP) located in exon 2 of PADI4 with RA in another Caucasian population; and (2) the association between PADI4 and anti-citrullinated...
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