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Article

Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus.

Proceedings of the National Academy of Sciences of the United States of America - 9 Oct 2007

Johansson Daniel X, Voisset Cécile, Tarr Alexander W, Aung Mie, Ball Jonathan K, Dubuisson Jean, Persson Mats A A

Abstract excerpt

One way to dissect the antibody response to an invading microorganism is to clone the antibody repertoire from immune donors and subsequently characterize the specific antibodies. Recently, methodological advances have allowed investigations of neutralizing antibodies against hepatitis C virus (HCV) in vitro. We have investigated three human mAbs, previously isolated from an individual infected with HCV of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17911260
DOI: 10.1073/pnas.0705522104
PMCID: PMC2042196

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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