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Article

Human monoclonal antibodies that inhibit binding of hepatitis C virus E2 protein to CD81 and recognize conserved conformational epitopes.

Journal of virology - 1 Nov 2000

Hadlock K G, Lanford R E, Perkins S, Rowe J, Yang Q, Levy S, Pileri P, Abrignani S, Foung S K

Abstract excerpt

The intrinsic variability of hepatitis C virus (HCV) envelope proteins E1 and E2 complicates the identification of protective antibodies. In an attempt to identify antibodies to E2 proteins from divergent HCV isolates, we produced HCV E2 recombinant proteins from individuals infected with HCV gen...

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Share to Antibodies, Monoclonal
Share to Antibodies, Viral
Share to Antigens, CD

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Conserved Sequence

Share to Epitope Mapping

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Share to Tetraspanin 28

Share to Viral Envelope Proteins

Source

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Identifiers

PMID: 11044085
DOI: 10.1128/jvi.74.22.10407-10416.2000
PMCID: PMC110915

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11044085-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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