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Article

Further genetic evidence implicates the vasopressin system in childhood-onset mood disorders.

The European journal of neuroscience - 1 Oct 2009

Dempster Emma L, Burcescu Irina, Wigg Karen, Kiss Eniko, Baji Ildiko, Gadoros Julia, Tamás Zsuzsanna, Kapornai Krisztina, Daróczy Gabriella, Kennedy James L, Vetró Agnes, Kovacs Maria, Barr Cathy L

Abstract excerpt

Studies in both animals and humans advocate a role for the vasopressin (AVP) system in the aetiology of depressive symptoms. Attention has particularly focused on the role of AVP in the overactivation of the hypothalamic-pituitary-adrenal (HPA)-axis in mood disorders. Elevated AVP plasma levels have been found in mood disorder patients, which are often positively correlated with the severity of symptoms. We...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19821843
DOI: 10.1111/j.1460-9568.2009.06930.x

Genes

AVP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Further genetic evidence implicates the vasopressin system in childhood-onset mood disorders.PMID 19821843Read ↗

Evidence of an association between the vasopressin V1b receptor gene (AVPR1B) and childhood-onset mood disorders.Semantic proximity Read ↗

The involvement of the vasopressin system in stress-related disorders.Semantic proximity Read ↗

No evidence of an association between two genes, EDN1 and ACE, and childhood-onset mood disorders.Semantic proximity Read ↗

A major SNP haplotype of the arginine vasopressin 1B receptor protects against recurrent major depression.Semantic proximity Read ↗

A complex selection signature at the human AVPR1B gene.Semantic proximity Read ↗

Mutation screen and association analysis of the glucocorticoid receptor gene (NR3C1) in childhood-onset mood disorders (COMD).Semantic proximity Read ↗

Association study of the adrenergic receptors and childhood-onset mood disorders in Hungarian families.Semantic proximity Read ↗

Epistatic interaction between CRHR1 and AVPR1b variants as a predictor of major depressive disorder.Semantic proximity Read ↗

Depression with above-normal plasma vasopressin: validation by relations with family history of depression and mixed anxiety and retardation.Semantic proximity Read ↗

Possible genetic association between vasopressin receptor 1B and child aggression.Semantic proximity Read ↗

A hypomorphic vasopressin allele prevents anxiety-related behavior.Semantic proximity Read ↗

Association analyses of depression and genes in the hypothalamus-pituitary-adrenal axis.Semantic proximity Read ↗

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