Article
Low utilization of circulating glucose after food withdrawal in Snell dwarf mice.
The Journal of biological chemistry - 30 Nov 2007
Brooks Natasha L, Trent Chad M, Raetzsch Carl F, Flurkey Kevin, Boysen Gunnar, Perfetti Michael T, Jeong Yo-Chan, Klebanov Simon, Patel Kajal B, Khodush Valerie R, Kupper Lawrence L, Carling David, Swenberg James A, Harrison David E, Combs Terry P
Abstract excerpt
Glucose metabolism is altered in long-lived people and mice. Although it is clear that there is an association between altered glucose metabolism and longevity, it is not known whether this link is causal or not. Our current hypothesis is that decreased fasting glucose utilization may increase longevity by reducing oxygen radical production, a potential cause of aging. We observed that whole body fasting glucose...
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