Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Food withdrawal lowers energy expenditure and induces inactivity in long-chain fatty acid oxidation-deficient mouse models.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jul 2014

Diekman Eugene F, van Weeghel Michel, Wanders Ronald J A, Visser Gepke, Houten Sander M

Abstract excerpt

Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is an inherited disorder of mitochondrial long-chain fatty acid β-oxidation (FAO). Patients with VLCAD deficiency may present with hypoglycemia, hepatomegaly, cardiomyopathy, and myopathy. Although several mouse models have been developed to aid in the study of the pathogenesis of long-chain FAO defects, the muscular phenotype is underexposed. To address...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acyl-CoA Dehydrogenase, Long-Chain
Share to Body Temperature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiomegaly

Share to Congenital Bone Marrow Failure Syndromes

Share to Fatty Liver

Share to Lipid Metabolism, Inborn Errors

Share to Muscular Diseases

Share to Rhabdomyolysis

Source

Identifiers

PMID: 24648546
DOI: 10.1096/fj.14-250241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Food withdrawal lowers energy expenditure and induces inactivity in long-chain fatty acid oxidation-deficient mouse models.PMID 24648546Read ↗

The cold truth: torpor as a confound in studies of caloric restrictionSemantic proximity Read ↗

A review of fatty acid oxidation disorder mouse models.Semantic proximity Read ↗

Tissue carnitine homeostasis in very-long-chain acyl-CoA dehydrogenase-deficient mice.Semantic proximity Read ↗

Induction of lipogenesis in white fat during cold exposure in mice: link to lean phenotype.Semantic proximity Read ↗

Tissue-specific strategies of the very-long chain acyl-CoA dehydrogenase-deficient (VLCAD-/-) mouse to compensate a defective fatty acid β-oxidation.Semantic proximity Read ↗

The effects of graded levels of calorie restriction: V. Impact of short term calorie and protein restriction on physical activity in the C57BL/6 mouseSemantic proximity Read ↗

A guide to analysis of mouse energy metabolism.Semantic proximity Read ↗

Deoxyguanosine kinase mutation F180S is associated with a lean phenotype in mice.Semantic proximity Read ↗

Low utilization of circulating glucose after food withdrawal in Snell dwarf mice.Semantic proximity Read ↗

Long-term correction of very long-chain acyl-coA dehydrogenase deficiency in mice using AAV9 gene therapy.Semantic proximity Read ↗

Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline.Semantic proximity Read ↗

Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.