Article
Identification of novel candidate genes for type 2 diabetes from a genome-wide association scan in the Old Order Amish: evidence for replication from diabetes-related quantitative traits and from independent populations.
Diabetes - 1 Dec 2007
Rampersaud Evadnie, Damcott Coleen M, Fu Mao, Shen Haiqing, McArdle Patrick, Shi Xiaolian, Shelton John, Yin Jing, Chang Yen-Pei C, Ott Sandra H, Zhang Li, Zhao Yiju, Mitchell Braxton D, O'Connell Jeffery, Shuldiner Alan R
Abstract excerpt
OBJECTIVE: We sought to identify type 2 diabetes susceptibility genes through a genome-wide association scan (GWAS) in the Amish. RESEARCH DESIGN AND METHODS: DNA from 124 type 2 diabetic case subjects and 295 control subjects with normal glucose tolerance were genotyped on the Affymetrix 100K si...
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