Article
Genome-wide association studies (GWAS): impact on elucidating the aetiology of diabetes.
Diabetes/metabolism research and reviews - 1 Oct 2011
Hakonarson Hakon, Grant Struan F A
Abstract excerpt
It has proven to be challenging to isolate the genes underlying the genetic components conferring susceptibility to type 1 and type 2 diabetes. Unlike previous approaches, 'genome-wide association studies' have extensively delivered on the promise of uncovering genetic determinants of complex diseases, with a number of novel disease-associated variants being largely replicated by independent groups. This review...
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