Differential regulation of interchromosomal copies of ToxR-induced genes.

Abstract excerpt

In Vibrio cholerae, ToxR transcriptionally activates a number of virulence genes in response to various environmental signals. In the present study, transcription profiling by macroarray was carried out with 13 pairs of genes, one copy of which is present in each chromosome under ToxR-inducing (pH 6.5, osmolarity 66 mmol/L, 30 degrees C) and ToxR-repressing (pH 8.5, osmolarity 300 mmol/L, 37 degrees C) conditions...

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