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Article

Disulfide bond formation and ToxR activity in Vibrio cholerae.

PloS one - 1 Jan 2012

Fengler Vera H I, Boritsch Eva C, Tutz Sarah, Seper Andrea, Ebner Hanna, Roier Sandro, Schild Stefan, Reidl Joachim

Abstract excerpt

Virulence factor production in Vibrio cholerae is complex, with ToxRS being an important part of the regulatory cascade. Additionally, ToxR is the transcriptional regulator for the genes encoding the major outer membrane porins OmpU and OmpT. ToxR is a transmembrane protein and contains two cysteine residues in the periplasmic domain. This study addresses the influence of the thiol-disulfide oxidoreductase system...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23144706
DOI: 10.1371/journal.pone.0047756
PMCID: PMC3483227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Disulfide bond formation and ToxR activity in Vibrio cholerae.PMID 23144706Read ↗

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