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Article

Mutations in the alpha and sigma-70 subunits of RNA polymerase affect expression of the mer operon.

Journal of bacteriology - 1 Mar 1997

Caslake L F, Ashraf S I, Summers A O

Abstract excerpt

The mercury resistance (mer) operon is transcribed from overlapping, divergent promoters: PR for the regulatory gene merR and P(TPCAD) for the structural genes merTPCAD. The dyadic binding site for MerR lies within the 19-bp spacer of the sigma70-dependent P(TPCAD). Unlike typical repressors, MerR does not exclude RNA polymerase from P(TPCAD) but rather forms an inactive complex with RNA polymerase at P(TPCAD)...

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Identifiers

PMID: 9045842
DOI: 10.1128/jb.179.5.1787-1795.1997
PMCID: PMC178895

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in the alpha and sigma-70 subunits of RNA polymerase affect expression of the mer operon.PMID 9045842Read ↗

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Cd(II)-responsive and constitutive mutants implicate a novel domain in MerR.Semantic proximity Read ↗

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