Article
Identification of an intramolecular interaction important for the regulation of GIT1 functions.
Molecular biology of the cell - 1 Dec 2007
Totaro Antonio, Paris Simona, Asperti Claudia, de Curtis Ivan
Abstract excerpt
G-protein coupled receptor kinase-interacting protein (GIT) proteins include an N-terminal Arf GTPase-activating protein domain, and a C terminus that binds proteins regulating adhesion and motility. Given their ability to form large molecular assemblies, the GIT1 protein must be tightly regulated. However, the mechanisms regulating GIT1 functions are poorly characterized. We found that carboxy-terminal-truncated...
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