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Article

Polymorphisms in the tissue factor pathway inhibitor gene are not associated with ischaemic stroke.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Oct 2007

Sayer Milly S, Cole Vanessa J, Adams Murray J, Baker Ross I, Staton Janelle M

Abstract excerpt

The present study aimed to determine whether four previously described polymorphisms found within the tissue factor pathway inhibitor (TFPI) gene are associated with free plasma TFPI levels or with TFPI activity as well as the risk of ischaemic stroke in stroke patients and control individuals. We conducted a case-control study of 162 first-ever ischaemic stroke cases and 170 randomly selected community control...

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Source

Identifiers

PMID: 17890962
DOI: 10.1097/MBC.0b013e3282dde994

Genes

TFPI

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Polymorphisms in the tissue factor pathway inhibitor gene are not associated with ischaemic stroke.PMID 17890962Read ↗

Genetic determinants of tissue factor pathway inhibitor plasma levels.Semantic proximity Read ↗

A new T-287C polymorphism in the 5' regulatory region of the tissue factor pathway inhibitor gene. Association study of the T-287C and C-399T polymorphisms with coronary artery disease and plasma TFPI levels.Semantic proximity Read ↗

High functional levels of thrombin-activatable fibrinolysis inhibitor are associated with an increased risk of first ischemic stroke.Semantic proximity Read ↗

Significant genetic association of a functional TFPI variant with circulating fibrinogen levels and coronary artery disease.Semantic proximity Read ↗

Functional characterization of polymorphisms in the human TFPI gene.Semantic proximity Read ↗

Polymorphisms in prothrombotic genes in young stroke patients in Greece: a case-controlled study.Semantic proximity Read ↗

Analysis of sequence variations in the promoter region of the human tissue factor pathway inhibitor 2 gene in apoplectic patients and blood donors.Semantic proximity Read ↗

Common genetic coagulation variants are not associated with ischemic stroke in a case-control study.Semantic proximity Read ↗

Tissue factor pathway inhibitor polymorphisms in women with and without a history of venous thrombosis and the effects of postmenopausal hormone therapy.Semantic proximity Read ↗

The 536C→T Transition in the Human Tissue Factor Pathway Inhibitor (TFPI) Gene Is Statistically Associated with a Higher Risk for Venous ThrombosisSemantic proximity Read ↗

The -33T-->C polymorphism in intron 7 of the TFPI gene influences the risk of venous thromboembolism, independently of the factor V Leiden and prothrombin mutations.Semantic proximity Read ↗

Polymorphisms and Risk of Ischemic Stroke (POLARIS) study: rationale and design.Semantic proximity Read ↗

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