Article
High functional levels of thrombin-activatable fibrinolysis inhibitor are associated with an increased risk of first ischemic stroke.
Journal of thrombosis and haemostasis : JTH - 1 Oct 2005
Leebeek F W G, Goor M P J, Guimaraes A H C, Brouwers G-J, Maat M P M, Dippel D W J, Rijken D C
Abstract excerpt
BACKGROUND AND OBJECTIVE: Several studies have suggested that thrombin-activatable fibrinolysis inhibitor (TAFI) levels are associated with the risk of arterial thrombosis, but results have been contradictory. We studied functional TAFI levels and TAFI gene polymorphisms in 124 patients with a recent ischemic stroke and 125 age- and sex-matched controls to establish the role of TAFI in ischemic stroke. METHODS...
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