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Article

Modulation of the conductance-voltage relationship of the BK Ca channel by mutations at the putative flexible interface between two RCK domains.

Biophysical journal - 15 Jan 2008

Kim Hyun-Ju, Lim Hyun-Ho, Rho Seong-Hwan, Bao Lin, Lee Ju-Ho, Cox Daniel H, Kim Do Han, Park Chul-Seung

Abstract excerpt

Calcium-dependent gating of the large-conductance Ca(2+)-activated K(+) (BK(Ca)) channel is conferred by the large cytosolic carboxyl terminus containing two domains of the regulator of K(+) conductance (RCK) and the high-affinity Ca(2+)-binding site (the Ca(2+)-bowl). In our previous study, we l...

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Identifiers

PMID: 17890381
DOI: 10.1529/biophysj.107.108738
PMCID: PMC2157237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17890381-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Modulation of the conductance-voltage relationship of the BK Ca channel by mutations at the putative flexible interface between two RCK domains.PMID 17890381Read ↗

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