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Article

Uncovering the mutation-fixation correlation in short lineages.

BMC evolutionary biology - 21 Sept 2007

Vallender Eric J, Lahn Bruce T

Abstract excerpt

BACKGROUND: We recently reported a highly unexpected positive correlation between the fixation probability of nonsynonymous mutations (estimated by omega) and neutral mutation rate (estimated by Ks) in mammalian lineages. However, this positive correlation was observed for lineages with relatively long divergence time such as the human-mouse lineage, and was not found for very short lineages such as the...

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Identifiers

PMID: 17883872
DOI: 10.1186/1471-2148-7-168
PMCID: PMC2071921

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