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Article

Association between migraine and the G1246A polymorphism in the hypocretin receptor 2 gene.

Headache - 1 Sept 2007

Schürks Markus, Limmroth Volker, Geissler Ingrid, Tessmann Grietje, Savidou Irini, Engelbergs Jörg, Kurth Tobias, Diener Hans-Christoph, Rosskopf Dieter

Abstract excerpt

BACKGROUND: The hypocretin receptor 2 (HCRTR2) G1246A polymorphism has been associated with the risk for cluster headache. Since the hypothalamic hypocretin/orexin system projects throughout the nervous system and affects multiple vegetative functions including generation of rhythmicity, vasomotion, autonomic symptoms as well as modulation of nociception, it may also be linked with migraine. OBJECTIVE: We thus...

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Source

Identifiers

PMID: 17883525
DOI: 10.1111/j.1526-4610.2007.00863.x

Genes

HCRTR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association between migraine and the G1246A polymorphism in the hypocretin receptor 2 gene.PMID 17883525Read ↗

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