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Article

The 1246G-->A polymorphism of the HCRTR2 gene is not associated with migraine.

Cephalalgia : an international journal of headache - 1 Aug 2007

Pinessi L, Binello E, De Martino P, Gallone S, Gentile S, Rainero I, Rivoiro C, Rubino E, Savi L, Valfrè W, Vaula G

Abstract excerpt

Studies in experimental animals have suggested that the hypocretin/orexin system may be involved in migraine pathophysiology. Using a case-control design study, we genotyped 246 migraine patients and 239 healthy controls for the 1246G-->A polymorphism of the hypocretin receptor 2 (HCRTR2) gene. G...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, G-Protein-Coupled

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Source

Identifiers

PMID: 17645762
DOI: 10.1111/j.1468-2982.2007.01347.x

Genes

HCRTR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17645762-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The 1246G-->A polymorphism of the HCRTR2 gene is not associated with migraine.PMID 17645762Read ↗

Association between migraine and the G1246A polymorphism in the hypocretin receptor 2 gene.Semantic proximity Read ↗

Evidence for an association between migraine and the hypocretin receptor 1 gene.Semantic proximity Read ↗

A polymorphism of the hypocretin receptor 2 gene is associated with cluster headache.Semantic proximity Read ↗

The G1246A polymorphism in the hypocretin receptor 2 gene is not associated with treatment response in cluster headache.Semantic proximity Read ↗

Haplotype analysis confirms the association between the HCRTR2 gene and cluster headache.Semantic proximity Read ↗

Association between the G1246A polymorphism of the hypocretin receptor 2 gene and cluster headache: a meta-analysis.Semantic proximity Read ↗

Cluster headache is associated with the G1246A polymorphism in the hypocretin receptor 2 gene.Semantic proximity Read ↗

Analysis of HCRTR2 Gene Variants and Cluster Headache in SwedenSemantic proximity Read ↗

Cluster headache and the hypocretin receptor 2 reconsidered: a genetic association study and meta-analysis.Semantic proximity Read ↗

Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population.Semantic proximity Read ↗

Genetics of cluster headache.Semantic proximity Read ↗

An investigation of the 5-HT2C receptor gene as a migraine candidate gene.Semantic proximity Read ↗

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