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Article

Haplotype analysis confirms the association between the HCRTR2 gene and cluster headache.

Headache - 1 Jul 2008

Rainero Innocenzo, Gallone Salvatore, Rubino Elisa, Ponzo Paola, Valfre Walter, Binello Eleonora, Fenoglio Pierpaola, Gentile Salvatore, Anoaica Mihaela, Gasparini Mauro, Pinessi Lorenzo

Abstract excerpt

BACKGROUND: Several studies suggested that genetic factors play a role in cluster headache (CH) susceptibility. We found a significant association between the 1246 G>A polymorphism of the hypocretin receptor-2 (HCRTR2) gene and the disease. This association was confirmed in a large study from Germany but was not replicated in a dataset of CH patients from Northern Europe. OBJECTIVE: The purpose of this study was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18399985
DOI: 10.1111/j.1526-4610.2008.01080.x

Genes

HCRTR2

Provenance

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