Evidence for an association between migraine and the hypocretin receptor 1 gene.

doi:10.1007/s10194-011-0314-8

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Article

Evidence for an association between migraine and the hypocretin receptor 1 gene.

The journal of headache and pain - 1 Apr 2011

Rainero Innocenzo, Rubino Elisa, Gallone Salvatore, Fenoglio Pierpaola, Picci Luigi Rocco, Giobbe Laura, Ostacoli Luca, Pinessi Lorenzo

Abstract excerpt

The aim of our study was to investigate whether genetic variants in the hypocretin receptor 1 (HCRTR1) gene could modify the occurrence and the clinical features of migraine. Using a case-control strategy we genotyped 384 migraine patients and 259 controls for three SNPs in the HCRTR1 gene. Genotypic and allelic frequencies of the rs2271933 non-synonymous polymorphism resulted different (χ(2)=9.872, p=0.007;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21344296
DOI: 10.1007/s10194-011-0314-8
PMCID: PMC3072499

Genes

HCRTR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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