Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NF-kappaB, IkappaB, and IRAK control glutamate receptor density at the Drosophila NMJ.

Neuron - 20 Sept 2007

Heckscher Elizabeth S, Fetter Richard D, Marek Kurt W, Albin Stephanie D, Davis Graeme W

Abstract excerpt

NF-kappaB signaling has been implicated in neurodegenerative disease, epilepsy, and neuronal plasticity. However, the cellular and molecular activity of NF-kappaB signaling within the nervous system remains to be clearly defined. Here, we show that the NF-kappaB and IkappaB homologs Dorsal and Cactus surround postsynaptic glutamate receptor (GluR) clusters at the Drosophila NMJ. We then show that mutations in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Electrophysiology
Share to I-kappa B Proteins
Share to Image Processing, Computer-Assisted

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-1 Receptor-Associated Kinases

Share to Membranes

Share to Neuromuscular Junction

Share to Receptors, Glutamate

Share to Synapses

Source

Open in PubMed Open full text

Identifiers

PMID: 17880891
DOI: 10.1016/j.neuron.2007.08.005
PMCID: PMC2701504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NF-kappaB, IkappaB, and IRAK control glutamate receptor density at the Drosophila NMJ.PMID 17880891Read ↗

Discs-large (DLG) is clustered by presynaptic innervation and regulates postsynaptic glutamate receptor subunit composition in Drosophila.Semantic proximity Read ↗

Muscle structure and innervation are affected by loss of Dorsal in the fruit fly, Drosophila melanogaster.Semantic proximity Read ↗

The Notch ligand E3 ligase, Mind Bomb1, regulates glutamate receptor localization in Drosophila.Semantic proximity Read ↗

A gain-of-function screen for genes that influence axon guidance identifies the NF-kappaB protein dorsal and reveals a requirement for the kinase Pelle in Drosophila photoreceptor axon targeting.Semantic proximity Read ↗

A novel function for the IκB inhibitor Cactus in promoting Dorsal nuclear localization and activity in the Drosophila embryo.Semantic proximity Read ↗

CDK-5 regulates the abundance of GLR-1 glutamate receptors in the ventral cord of Caenorhabditis elegans.Semantic proximity Read ↗

A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila.Semantic proximity Read ↗

The anaphase-promoting complex regulates the abundance of GLR-1 glutamate receptors in the ventral nerve cord of C. elegans.Semantic proximity Read ↗

Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation.Semantic proximity Read ↗

Drosophila Nesprin-1 controls glutamate receptor density at neuromuscular junctions.Semantic proximity Read ↗

Regulated nuclear import of Rel proteins in the Drosophila immune response.Semantic proximity Read ↗

C-terminal Src Kinase Gates Homeostatic Synaptic Plasticity and Regulates Fasciclin II Expression at the Drosophila Neuromuscular Junction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.