Article
The G2019S LRRK2 mutation is uncommon amongst Greek patients with sporadic Parkinson's disease.
European journal of neurology - 1 Oct 2007
Kalinderi K, Fidani L, Bostantjopoulou S, Katsarou Z, Kotsis A
Abstract excerpt
Parkinson's disease (PD) is the second most common neurodegenerative disorder affecting approximately 2% of the population >60 years of age. Although, the etiology of PD is still unknown, the genetic background of the disease has been documented. Recently, a mutation in the LRRK2 gene, G2019S, was associated with 3-41% and 1-2% of familial and sporadic PD, respectively suggesting a pivotal role of LRRK2 in PD. In...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
