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Article

Prevalence of the LRRK2 G2019S mutation in a UK community based idiopathic Parkinson's disease cohort.

Journal of neurology, neurosurgery, and psychiatry - 1 May 2006

Williams-Gray C H, Goris A, Foltynie T, Brown J, Maranian M, Walton A, Compston D A S, Sawcer S J, Barker R A

Abstract excerpt

The LRRK2 G2019S mutation is the commonest genetic cause of Parkinson's disease (PD) identified to date, although estimates of its prevalence in idiopathic disease vary considerably. Our objectives were to determine G2019S mutation frequency in an unselected, community based cohort of idiopathic PD cases from the UK and to describe phenotypic characteristics among carriers. The mutation was present in two of 519...

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Identifiers

PMID: 16614029
DOI: 10.1136/jnnp.2005.085019
PMCID: PMC2117467

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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