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Article

Telomerase recognizes G-quadruplex and linear DNA as distinct substrates.

Biochemistry - 9 Oct 2007

Oganesian Liana, Graham Mark E, Robinson Phillip J, Bryan Tracy M

Abstract excerpt

Telomeric DNA can assemble into a nonlinear, higher-order conformation known as a G-quadruplex. Here, we demonstrate by electrospray ionization mass spectrometry that the two repeat telomeric sequence d(TGGGGTTGGGGT) from Tetrahymena thermophila gives rise to a novel parallel four-stranded G-quad...

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Source

Identifiers

PMID: 17877374
DOI: 10.1021/bi700993q

Genes

TERT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17877374-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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