Article
A genome-wide association screen identifies regions on chromosomes 1q25 and 7p21 as risk loci for sporadic prostate cancer.
Prostate cancer and prostatic diseases - 1 Jan 2008
Nam R K, Zhang W W, Loblaw D A, Klotz L H, Trachtenberg J, Jewett M A S, Stanimirovic A, Davies T O, Toi A, Venkateswaran V, Sugar L, Siminovitch K A, Narod S A
Abstract excerpt
We conducted a genome-wide association study of 3090 sporadic prostate cancer patients and controls using the Affymetrix 10 000 SNP GeneChip. Initial screening of 40 prostate cancer cases and 40 non-cancer controls revealed 237 SNPs to be associated with prostate cancer (P<0.05). Among these SNPs...
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