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Article

P21WAF1/CIP1 expression in colorectal carcinomas is related to Kras mutations and prognosis.

European journal of gastroenterology & hepatology - 1 Oct 2007

Mitomi Hiroyuki, Ohkura Yasuo, Fukui Naoshi, Kanazawa Hideki, Kishimoto Ichiro, Nakamura Takatoshi, Yokoyama Kaoru, Sada Miwa, Kobayashi Kiyonori, Tanabe Satoshi, Saigenji Katsunori

Abstract excerpt

BACKGROUND/AIM: P21WAF1/CIP1 is a cyclin-dependent kinase inhibitor activated by p53 to produce cell cycle arrest. A consensus has not been reached concerning the prognostic value of p21WAF1/CIP1 expression in colorectal cancers. PATIENTS/METHODS: P21WAF1/CIP1 expression was determined immunohistochemically in a series of 211 cases of colorectal carcinomas, together with its relation to p53, bcl-2, cell turnover...

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Identifiers

PMID: 17873613
DOI: 10.1097/MEG.0b013e3282e1c5f3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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