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Article

p21waf1/cip1 and transforming growth factor beta 1 protein expression correlate with survival in non-small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 1998

Bennett W P, el-Deiry W S, Rush W L, Guinee D G, Freedman A N, Caporaso N E, Welsh J A, Jones R T, Borkowski A, Travis W D, Fleming M V, Trastek V, Pairolero P C, Tazelaar H D, Midthun D, Jett J R, Liotta L A, Harris C C

Abstract excerpt

p21waf1/cip1 encodes a cyclin-dependent kinase inhibitor that is transcriptionally activated by the p53 tumor suppressor gene, transforming growth factor beta 1 (TGF-beta 1), AP2, and other pathways. Because p21waf1/cip1, p53, and TGF-beta 1 all regulate apoptosis and the cell cycle, we tested the hypothesis that their relative protein levels would correlate with biological features including the survival of...

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PMID: 9626468

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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