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Article

The IL23 axis plays a key role in the pathogenesis of IBD.

Gut - 1 Oct 2007

McGovern Dermot, Powrie Fiona

Abstract excerpt

Exciting new results from a genetic study in humans and functional studies in mice have pinpointed interleukin 23 (IL23) and its receptor as a key pathway in the pathogenesis of inflammatory bowel disease (IBD). These findings reveal a hitherto unappreciated role for the IL23 axis in intestinal inflammation and may open new avenues for development of therapeutic strategies in IBD.

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Identifiers

PMID: 17872562
DOI: 10.1136/gut.2006.115402
PMCID: PMC2000291

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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