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Article

Integrating metabolomics and phenomics with systems models of cardiac hypoxia.

Progress in biophysics and molecular biology - 1 Jan 2000

Feala Jacob D, Coquin Laurence, Paternostro Giovanni, McCulloch Andrew D

Abstract excerpt

Hypoxia is the major cause of necrotic cell death in myocardial infarction. Cellular energy supply and demand under hypoxic conditions is regulated by many interacting signaling and transcriptional networks, which complicates studies on individual proteins and pathways. We apply an integrated systems approach to understand the metabolic and functional response to hypoxia in muscle cells of the fruit fly...

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PMID: 17870149
DOI: 10.1016/j.pbiomolbio.2007.07.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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