Article
Spontaneous central apneas occur in the C57BL/6J mouse strain.
Respiratory physiology & neurobiology - 1 Jan 2008
Stettner Georg M, Zanella Sébastien, Huppke Peter, Gärtner Jutta, Hilaire Gérard, Dutschmann Mathias
Abstract excerpt
Despite the clinical significance of central apneas in a wide range of disorders little is known about their pathogenesis. Research in this field has been hindered by the lack of appropriate animal models. Our goal was to determine whether the C57BL/6J mouse strain, which has an inherited predisp...
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