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Article

Spontaneous central apneas occur in the C57BL/6J mouse strain.

Respiratory physiology & neurobiology - 1 Jan 2008

Stettner Georg M, Zanella Sébastien, Huppke Peter, Gärtner Jutta, Hilaire Gérard, Dutschmann Mathias

Abstract excerpt

Despite the clinical significance of central apneas in a wide range of disorders little is known about their pathogenesis. Research in this field has been hindered by the lack of appropriate animal models. Our goal was to determine whether the C57BL/6J mouse strain, which has an inherited predisposition for dysrhythmic breathing, exhibits spontaneous apneas. In vivo plethysmography of unanesthetized, unrestrained...

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Identifiers

PMID: 17869191
DOI: 10.1016/j.resp.2007.07.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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