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Article

C57BL/6J mouse apolipoprotein A2 gene is deterministic for apnea.

Respiratory physiology & neurobiology - 1 Jan 2017

Gillombardo Carl B, Darrah Rebecca, Dick Thomas E, Moore Michael, Kong Nathan, Decker Michael J, Han Fang, Yamauchi Motoo, Dutschmann Mathias, Azzam Sausan, Strohl Kingman P

Abstract excerpt

RATIONALE: Brainstem apolipoprotein AII (apoa2) mRNA expression correlates with apnea in breathing present in the adult C57Bl/6J (B6) sleep apnea model. OBJECTIVES: To test the hypothesis that the B6 apoa2 gene contributes to the trait, we performed plethysmographic testing in apoa2 knock out (KO: -/-) mice, an in situ brainstem-spinal cord preparation comparing KO to WT (+/+) mice, and B6xDBA recombinant inbred...

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Identifiers

PMID: 27756649
DOI: 10.1016/j.resp.2016.10.006
PMCID: PMC5136301

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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